Plot: 10 years from now, vampires make up the vast majority of the population with only 5% of the human race remaining. This presents particular challenges as the vampires' food supply - human blood - is dwindling and rationing is now the norm. There is growing evidence that vampires deprived of an adequate blood supply are themselves evolving into wild, vile creatures that attack anyone and anything in order to survive. Dr. Edward Dalton, a vampire and hematologist who works for a pharmaceutical firm, has been working on finding an artificial blood supply that will meet the vampire society's needs. He is sympathetic to humans and sees his work as a way of alleviating their suffering but his views on finding a solution change considerably when he meets someone who found a way to transform himself from being a vampire to again take human form.
Alternative Plot: Ten years after a plague turns most of the world's population into vampires, a critical blood shortage causes panic and gruesome mutations among the reanimated. Edward (Ethan Hawke), a vampire hematologist, tries to develop a blood substitute when he meets Lionel (Willem Dafoe) and Audrey (Claudia Karvan), two fugitive humans who claim to have a possible cure. Edward casts his lot with them in the hope of perfecting the cure before it's too late.
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