Plot: The only sister of Jack, Lily Romero, tries to commit suicide after the death of their mother. Jack is in despair since Lily is sent to a mental institution and Jack is not allowed to visit her. Jack pretends to be insane and is arrested and sent to the same asylum with the intention of rescuing Lily from the place. Sooner Jack learns that the administrator, Dr. Gianetti, is a deranged scientist that is using the patients like guinea pigs, forcing them to use the experimental drug Orpheus. Further, the side effect is turning patients and staff into flesh-eating zombies. But Lily and Jack are trapped in the mental institution and there is no way out for them.
Alternative Plot: Staffers at a mental institution conduct an experiment that turns subjects into vicious killers.
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