Plot: After an accident in a tunnel, a forensics expert is left as a quadriplegic who is able only to move his head and one finger. Setting his finger to a computer, he is able to manipulate his environment with the help of a loving nurse. Even so, fearing seizures that could leave him a vegetable, he plans his "transition" with the help of a hesitational doctor friend. That all changes when he is confronted with clues from a serial killer that obviously are pointed to forensics investigation. The case clearly re-invokes his interest in life. A sharp, young cop's quick thinking saves the first crime scene. Recognizing her talent for forensics, he brings her unwillingly into forensics detection. Through radio contact, she becomes his eyes and legs on the scene. Michael Rooker also appears as the police captain, who has bungled earlier killings by the serial killer and is more interested in the press than in good police work. Ed O'Neill and Luis Guzman are support staff who aid Washington and run interference with Rooker.
Alternative Plot: Policewoman Amelia Donaghy (Angelina Jolie) is in hot pursuit of a serial murderer whose calling card is a small shard of bone extracted from each of his victims. Unable to decipher the cryptic clues the killer leaves behind at the scene of the crime, Amelia calls upon quadriplegic forensic criminology expert Lincoln Rhyme (Denzel Washington) to help. With Amelia acting as Rhyme's able-bodied go-between, the pair piece together disparate clues, hoping they will learn who the next victim is.
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